Dynamic Force Measurement in Preformulation of Solid Dosage Forms
نویسنده
چکیده
The topic of this article is the compression physics of different gum bases which can be used to prepare chewing gumtablets by direct compression. Three different gum bases, Pharmagum® C, M and S, were tested alone and in differentcombinations. The preparations were compressed with a Korsch EK0 eccentric tableting machine at compressionforces of 5, 7.5, 10, 12.5 and 15 kN. The compression and breaking processes and the physical parameters of thetablets were investigated. The results revealed that increase of the compression force did not significantly changethe studied parameters of the tablets.
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